05/30/2026
20 g/day creatine for 8 weeks in 20 people with Alzheimer's disease resulted in significant improvements in cognitive abilities in a landmark study in the Alzheimer’s and Dementia Association Journal. This is a big deal. Impaired brain energy metabolism, including dysfunction in the creatine system, is a likely contributor to the development and progression of Alzheimers disease making it a compelling target for treatment. These patients saw an increase in both circulating Creatine and Brain creatine at both 4 and 8 weeks and this corresponded to improvements in cognitive function. We have already been recommending Creatine in our Integrative Health clinic in Brain condition but studies like these go a long way to support it usage. (Not medical advice) It may offer a cost-effective therapeutic strategy for improving brain energy metabolism in AD by targeting the brain Creatine system. In addition supplementation may be paired with other very safe modalities such as transcranial infrared light therapy (as we are doing in our clinics) to achieve even more profound improvements and this is an area where further research is very much needed. With the number of people projected to be suffering from dementia expected to triple by 2050 we need solutions to this devastating illness to advance very quickly Dr S
