09/01/2026
⚠️ IMPORTANT NOTICE: PRESCRIPTION DRUG DROP BOX TEMPORARILY UNAVAILABLE
Until further notice, the De Soto Police Department is unable to accept prescription medications in the drop box located in our lobby.
Please do not leave medications outside the drop box or elsewhere in the lobby. Residents may use one of the following alternate drop-off locations:
Arnold Police Department
2101 Jeffco Blvd., Arnold
(636) 296-3204
Open 24 hours
Hillsboro Police Department
101 Main Street, Hillsboro
(636) 797-3334, Ext. 2
Monday–Friday, 8 a.m.–4 p.m.
Call dispatch after hours
Big River Ambulance – Station No. 1
6321 Lorens Lane, Cedar Hill
(636) 274-3964
Monday–Friday, 8 a.m.–5 p.m.
Jefferson College Police Department
802 Mel Carnahan Drive, Apt. 214, Hillsboro
(636) 481-3500
Open 24 hours
Crystal City Police Department
130 Mississippi Avenue, Crystal City
(636) 937-4614
Monday–Friday, 8 a.m.–4:30 p.m.
North Zone Sheriff’s Office
26 Dillon Plaza Drive, High Ridge
Located in Dillon Plaza
(636) 797-3210
Monday–Friday, 9 a.m.–6 p.m.
Pevely Police Department
401 West Main Street, Pevely
(636) 475-4498
Open 24 hours
Seckman Substation
3055 Lions Den Road, Imperial
(636) 797-6066
Monday–Friday, 9 a.m.–5 p.m.
Festus Police Department
100 Park Avenue, Festus
(636) 937-3646
Monday–Friday, 8 a.m.–5 p.m.
We recommend calling the location before visiting to confirm that its drop box is currently available. We apologize for the inconvenience and will notify the public when our drop box is available again.
Thank you for your patience and cooperation.