中央研究院 分子生物研究所 Institute of Molecular Biology

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中央研究院 分子生物研究所 Institute of Molecular Biology 中央研究院 分子生物研究所 The preparatory office of The Institute of Molecular Biology was founded in December of 1982. Drs. Ru-Chih C. Dr. C. C. Dr. James C.-K.

Building construction was completed and research started on July 1, 1986 under the directorship of Dr. James Wang. Huang, Ray Wu, and Chien Ho served as interim directors during 1987-1991. Wang of UCSF assumed the directorship from September 1991 to February 1994. The Institute completed its preparatory status and officially established itself as an Institute on March 1, 1993. Shen has been the Director from 1995- 2004. Dr. Meng-Chao Yao assumed the Directorship from February of 2004.

[TIGP-MCB Program] Professional Development for A Graduate Student-Career Opportunity Lecture SeriesApplied Research/CRO...
14/05/2026

[TIGP-MCB Program] Professional Development for A Graduate Student-Career Opportunity Lecture Series

Applied Research/CRO on May 21st

🧬繼趙裕展老師分享 從基礎到應用的實戰經驗後, 下周四的PDGS 講座將帶你前往生技產業前線!

✨ 一次掌握兩大熱門職涯方向:
🔹 應用研究與 Pre-clinical 開發
🔹 CRO 臨床試驗與產業實務

🎤 講者陣容:
👨‍🔬 周民元 副所長(工研院 ITRI)
分享蛋白質工程、Collabody 平台與生醫創新應用

👨‍💼 胡瑞坤 總經理(A2 Healthcare)
解析 CRO 產業、法規趨勢與跨領域團隊管理

📍 5/21(四)14:00–15:50
🏢 中研院分生所一樓演講廳
👥 歡迎所有對生技產業有興趣的師生與研究人員參加!

一起探索 PhD 職涯新可能 🚀

#生醫產業 #職涯發展 #應用研究 #工研院

🧬 Wondering what’s next after your PhD?
Join the PDGS Seminar and explore career opportunities in the biotech industry!

✨ Two key topics in one session:
🔹 Applied Research & Pre-clinical Development
🔹 CRO Industry, Clinical Trials & Industry Practice

🎤 Speakers:
👨‍🔬 Dr. Min-Yuan Chou (ITRI)
Sharing insights into protein engineering, the Collabody platform, and biomedical innovation

👨‍💼 Mr. Simon Hu (A2 Healthcare)
Discussing CRO operations, regulatory trends, and multidisciplinary team leadership

📍 Thu. May 21 |14:00–15:50
🏢 IMB 1F Auditorium
👥 Open to all students, faculty, TAs, and researchers interested in biotech careers!

Discover new horizons for your PhD career 🚀

【中研院分子生物研究所學術講座】🗣主講人:Dr. Lingchong Youhttps://www.youlab.bio/🦚講題:Antibiotic response and gene transfer in microbial comm...
14/05/2026

【中研院分子生物研究所學術講座】
🗣主講人:Dr. Lingchong You
https://www.youlab.bio/
🦚講題:Antibiotic response and gene transfer in microbial communities
⏰時間:2026年5月21日(星期四)11:00am-12:00pm
🏛️地點:中央研究院分子生物研究所1F演講廳
⚜️主持人: Dr. Wei-Hsiang Lin 林暐翔 (分生所助研究員) https://www.imb.sinica.edu.tw/ch/faculty/profile/whlin.html
🔔誠摯邀請您前來參加!
==========================================
【AS IMB Seminar】
🗣Speaker: Dr. Lingchong You
https://www.youlab.bio/
🦚Title: Antibiotic response and gene transfer in microbial communities
⏰Time: 2026/5/21 (Thursday) 11:00am-12:00pm
🏛️Venue: IMB 1F Auditorium
⚜️Host: Dr. Wei-Hsiang Lin (IMB Assistant Research Fellow) https://www.imb.sinica.edu.tw/en/faculty/profile/whlin.html
🔔Your participation is cordially welcome!

【中研院分子生物研究所學術講座】🗣主講人:Dr. Yuichi Wakamoto 若本祐一https://webpark1706.sakura.ne.jp/en/🦚講題:Global stoichiometric architecture ...
13/05/2026

【中研院分子生物研究所學術講座】
🗣主講人:Dr. Yuichi Wakamoto 若本祐一
https://webpark1706.sakura.ne.jp/en/
🦚講題:Global stoichiometric architecture dictates the intracellular propagation of genetic perturbations: Insights from Taman-omics
⏰時間:2026年5月20日(星期三)11:00am-12:00pm
🏛️地點:中央研究院分子生物研究所1F演講廳
⚜️主持人: Dr. Keita Kamino 神野圭太(分生所助研究員) https://www.imb.sinica.edu.tw/ch/faculty/profile/keita.html
🔔誠摯邀請您前來參加!
==========================================
【AS IMB Seminar】
🗣Speaker: Dr. Yuichi Wakamoto 若本祐一
https://webpark1706.sakura.ne.jp/en/
🦚Title: Global stoichiometric architecture dictates the intracellular propagation of genetic perturbations: Insights from Taman-omics
⏰Time: 2026/5/20 (Wednesday) 11:00am-12:00pm
🏛️Venue: IMB 1F Auditorium
⚜️Host: Dr. Keita Kamino (IMB Assistant Research Fellow) https://www.imb.sinica.edu.tw/en/faculty/profile/keita.html
🔔Your participation is cordially welcome!

【Upcoming Lecture: From Basic to Application — A Success Story in Academic Translation】🧬✨Is the commercialization of aca...
12/05/2026

【Upcoming Lecture: From Basic to Application — A Success Story in Academic Translation】🧬✨

Is the commercialization of academic research always an uphill battle? The key lies in having the ”right strategy”! 💡
學術研究的商業化轉型總是非常困難嗎?關鍵在於「正確的策略」! 💡

We are happy to invite Dr. Yu-Chan Chao to share his insights on translating basic research into a biotech startup. This event is hosted by the TIGP-MCB program as part of the Professional Development for A Graduate Student series. 🚀

Using baculovirus-based vaccine as a real-world example, this lecture will provide an in-depth exploration of the key practical steps required for successful technology translation. 🔬

本次講座邀請到 趙裕展老師 分享如何將基礎研究轉化為生技新創公司。講座將以 桿狀病毒疫苗 (Baculovirus-based vaccine) 為實例,深度解析在實務上轉譯如何成功的每一步。 🔬

📍 Event Information / 活動資訊
• Topic: From Basic to Application
• Date & Time: May 14 (Thu) 14:00 – 15:50
• Venue: 1F Auditorium, IMB
• Speaker: Dr. Yu-Chan Chao (Director, BacuNova BioTech, Co., Ltd.)

Don't miss this chance to learn about biotech industrialization and career development! 誠摯歡迎所有對生技產業與職涯發展感興趣的朋友參與!

【IMB研究成果發表-陳律佑副研究員】癌細胞永生的秘密:孤兒核受體透過TRIM28 啟動端粒延長機制https://www.sinica.edu.tw/news_content/36/3784一般細胞在分裂多次後,染色體端粒會逐漸縮短,最後...
12/05/2026

【IMB研究成果發表-陳律佑副研究員】
癌細胞永生的秘密:孤兒核受體透過TRIM28 啟動端粒延長機制
https://www.sinica.edu.tw/news_content/36/3784

一般細胞在分裂多次後,染色體端粒會逐漸縮短,最後細胞會停止分裂。然而,癌細胞會利用「替代性端粒延長機制(Alternative Lengthening of Telomeres, 簡稱ALT)維持端粒長度,避免細胞老化並持續分裂。

本院分生所陳律佑副研究員研究團隊發現,ALT的啟動與端粒上的「H3K9me3異質染色標記」密切相關,這種標記代表端粒DNA結構變得更為緊密,也被視為是ALT運作的關鍵。研究指出,孤兒核受體(orphan nuclear receptors)會將轉錄共抑制因子(TRIM28)帶到端粒位置,促使端粒染色質轉變為H3K9me3標記的異染色質狀態,進而改變端粒結構並啟動ALT機制,使癌細胞得以維持端粒長度且持續分裂。研究進一步發現,TRIM28是ALT活化的必要因子。除了孤兒核受體外,KRAB domain亦可透過TRIM28誘導類似ALT現象,顯示ALT啟動與染色質異質狀態密切相關。

論文第一作者為本院國際研究生學程「分子與細胞生物學」(TIGP-MCB)博士生蔡佳岑。研究經費由本院關鍵突破計畫與國科會共同支持。研究成果已於2026年3月31日發表於《歐洲分子生物學組織期刊》(The EMBO Journal)。

【GSB-IMB Joint Seminar Series】🗣主講人:Dr. Gene Robinson (University of Illinois at Urbana-Champaign) https://sib.illinois.e...
07/05/2026

【GSB-IMB Joint Seminar Series】
🗣主講人:Dr. Gene Robinson (University of Illinois at Urbana-Champaign) https://sib.illinois.edu/directory/profile/generobi
🦚講題:Genomic Pillars of the Social Brain: Lessons from the Honey Bee
⏰時間:2026年5月19日(星期二)11am-12pm
🏛️地點:中央研究院分子生物研究所1F演講廳
⚜️主持人:Dr. Leu, Jun-Yi 呂俊毅 (分生所特聘研究員) https://www.imb.sinica.edu.tw/ch/faculty/profile/jleu.html
🔔誠摯邀請您前來參加!
==========================================
【GSB-IMB Joint Seminar Series】
🗣Speaker: Dr. Gene Robinson (University of Illinois at Urbana-Champaign) https://sib.illinois.edu/directory/profile/generobi
🦚Title: Genomic Pillars of the Social Brain: Lessons from the Honey Bee
⏰Time: 2026/5/19 (Tuesday) 11am-12pm
🏛️Venue: IMB 1F Auditorium
⚜️Host: Dr. Leu, Jun-Yi (IMB Distinguished Research Fellow) https://www.imb.sinica.edu.tw/en/faculty/profile/jleu.html
🔔Your participation is cordially welcome!

06/05/2026
【中研院分子生物研究所學術講座】🗣主講人:Dr. Fumi Kubo (RIKEN Center for Brain Science)http://kubolab.jp/wp/en/🦚講題:Neural mechanisms underl...
04/05/2026

【中研院分子生物研究所學術講座】
🗣主講人:Dr. Fumi Kubo (RIKEN Center for Brain Science)
http://kubolab.jp/wp/en/
🦚講題:Neural mechanisms underlying visual processing and behavioral control in zebrafish
⏰時間:2026年5月12日(星期二)11:00am-12:00pm
🏛️地點:中央研究院分子生物研究所1F演講廳
⚜️主持人:Dr. Kuo-Hua Huang 黃國華(分生所助研究員) https://www.imb.sinica.edu.tw/ch/faculty/profile/kuohuahuang.html
🔔誠摯邀請您前來參加!
==========================================
【AS IMB Seminar】
🗣Speaker: Dr. Fumi Kubo (RIKEN Center for Brain Science)
http://kubolab.jp/wp/en/
🦚Title: Neural mechanisms underlying visual processing and behavioral control in zebrafish
⏰Time: 2026/5/12 (Tuesday) 11:00am-12:00pm
🏛️Venue: IMB 1F Auditorium
⚜️Host: Dr. Kuo-Hua Huang (IMB Assistant Research Fellow) https://www.imb.sinica.edu.tw/en/faculty/profile/kuohuahuang.html
🔔Your participation is cordially welcome!

【PhD Career Opportunities 2026】學術 vs. 業界?你的職涯全地圖自本周起, 每周四將由國際研究生分子與細胞生物學學程 (TIGP-MCB Program) 與本所學生助理博士後聯誼會合辦職涯發展系列講座 📍別...
20/04/2026

【PhD Career Opportunities 2026】學術 vs. 業界?你的職涯全地圖

自本周起, 每周四將由國際研究生分子與細胞生物學學程 (TIGP-MCB Program) 與本所學生助理博士後聯誼會合辦職涯發展系列講座

📍別讓想像限制了你的職涯!
從 AI 應用、學術路徑到國際藥廠,帶你直擊博班生或畢業後的多元發展路徑。

🚀 課程亮點 Highlights:
• Academia: 學術教職與博後生存攻略 🎓
• Applied Research / CRO: 應用研究與臨床試驗轉型 🧪
• Big Pharma: 國際大藥廠(Roche/AHEAD)職涯 💊
• Industry Service: 產業供應鏈(ThermoFisher)專業職位 🧬

📅 活動資訊 Info:
• Time: 2026/04/23 – 06/11 (Every Thu.) 14:00 – 15:50
• Venue: IMB 1F Auditorium
• Speakers: Experts from IMB, ITRI, Roche, ThermoFisher, and more

#中研院 #生技職涯 #職涯發展

【中研院分子生物研究所學術講座】🗣主講人:Dr. Li-Hao Huang 黃立豪 (Associate Professor, Institute of Metabolism and Integrative Biology, Fudan U...
13/04/2026

【中研院分子生物研究所學術講座】
🗣主講人:Dr. Li-Hao Huang 黃立豪 (Associate Professor, Institute of Metabolism and Integrative Biology, Fudan University)
https://imib.fudan.edu.cn/imiben/34/7e/c23203a275582/page.htm
🦚講題:Skin inflammation rewires gut lipid metabolism: A novel pathway to inflammatory bowel disease comorbidity
⏰時間:2026年4月15日(星期三)11:00am-12:00pm
🏛️地點:中央研究院分子生物研究所1F演講廳
⚜️主持人:Dr. Wei-Le Wang 王維樂(分生所助研究員) https://www.imb.sinica.edu.tw/ch/faculty/profile/wangweile.html
🔔誠摯邀請您前來參加!
==========================================
【AS IMB Seminar】
🗣Speaker: Dr. Li-Hao Huang (Associate Professor, Institute of Metabolism and Integrative Biology, Fudan University)
https://imib.fudan.edu.cn/imiben/34/7e/c23203a275582/page.htm
🦚Title: Skin inflammation rewires gut lipid metabolism: A novel pathway to inflammatory bowel disease comorbidity
⏰Time: 2026/4/15 (Wednesday) 11:00am-12:00pm
🏛️Venue: IMB 1F Auditorium
⚜️Host: Dr. Wei-Le Wang 王維樂 (IMB Assistant Research Fellow) https://www.imb.sinica.edu.tw/en/faculty/profile/wangweile.html
🔔Your participation is cordially welcome!

【中研院分子生物研究所學術講座】🗣主講人:Dr. Ian Ehrenreich (Divisional Dean for the Life Sciences, Professor, Department of Biological Scie...
02/04/2026

【中研院分子生物研究所學術講座】
🗣主講人:Dr. Ian Ehrenreich (Divisional Dean for the Life Sciences, Professor, Department of Biological Sciences, University of Southern California)
https://dornsife.usc.edu/ehrenreich-lab/
🦚講題:Building chromosomes to study evolution and the minimum requirements for eukaryotic life
⏰時間:2026年4月7日(星期二)11:00am-12:00pm
🏛️地點:中央研究院分子生物研究所1F演講廳
⚜️主持人: Dr. Jun-Yi Leu 呂俊毅 (分生所特聘研究員) https://www.imb.sinica.edu.tw/ch/faculty/profile/jleu.html
🔔誠摯邀請您前來參加!
==========================================
【AS IMB Seminar】
🗣Speaker: Dr. Ian Ehrenreich (Divisional Dean for the Life Sciences, Professor, Department of Biological Sciences, University of Southern California)
https://dornsife.usc.edu/ehrenreich-lab/
🦚Title: Building chromosomes to study evolution and the minimum requirements for eukaryotic life
⏰Time: 2026/4/7 (Tuesday) 11:00am-12:00pm
🏛️Venue: IMB 1F Auditorium
⚜️Host: Dr. Jun-Yi Leu (IMB Distinguished Research Fellow) https://www.imb.sinica.edu.tw/en/faculty/profile/jleu.html
🔔Your participation is cordially welcome!

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