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MINDD Foundation promotes an integrative approach to healthcare for the whole family with a focus on Functional Medicine, nutrition, neuro-development and allied therapies.

27/10/2026

The effects of antibiotics on the gut microbiome can persist for weeks, months, and in some cases, even years.

A narrative review examined how antibiotic use can alter the gut microbiota across different stages of life.

Antibiotics target harmful bacteria, but they can also reduce beneficial microbes and overall microbial diversity. This disruption, known as dysbiosis, can affect immune function, metabolism and the ability of pathogenic or antibiotic-resistant species to establish themselves.

The review found that these effects can differ throughout the lifespan. Antibiotic exposure during pregnancy and infancy may alter the developing microbiome, while in adults some microbial changes can remain long after a course of antibiotics has ended.
Antibiotic-induced changes may also affect bile acid metabolism, short-chain fatty acid production and other pathways involved in insulin sensitivity, weight regulation and susceptibility to infection.

The researchers also discuss probiotics and prebiotics as potential strategies for supporting microbial recovery, while highlighting the need to better understand how to protect the microbiome alongside appropriate antibiotic use.

🔗 Read the full article here: https://mindd.org/research/10-1016-j-medmic-2024-100106/

Were you aware that antibiotics could affect the gut microbiome long after treatment ends? Let us know below or share this research with someone who may find it useful.

22/10/2026

Can a structured mindfulness program reduce anxiety as effectively as medication?

A randomised clinical trial comparing mindfulness-based stress reduction with escitalopram, a commonly prescribed anxiety medication, found that both treatments produced meaningful reductions in anxiety symptoms.

Adults diagnosed with anxiety disorders were randomly assigned to either an eight-week mindfulness-based stress reduction program or escitalopram, with their anxiety severity assessed by blinded evaluators.

The mindfulness intervention was found to be as effective as escitalopram in reducing anxiety severity. There was also a notable difference in adverse events: these were considerably more common among participants taking medication. A small proportion discontinued escitalopram because of side effects, while no participants in the mindfulness group withdrew for this reason.

The findings suggest that a standardised mindfulness-based intervention may offer a viable treatment option for people with anxiety disorders.

🔗 Read the full article here: https://mindd.org/research/10-1001-jamapsychiatry-2022-3679/

20/10/2026

Higher consumption of ultra-processed foods may be associated with an increased risk of developing multiple chronic diseases.

A large prospective study followed more than 266,000 adults who were initially free of cancer, cardiovascular disease and type 2 diabetes to investigate whether ultra-processed food consumption predicted the development of multimorbidity.

Over an average 11.2 years of follow-up, higher consumption of ultra-processed foods was associated with an increased risk of developing multimorbidity involving cancer and cardiometabolic disease.

The strongest associations were observed for animal-based ultra-processed products and sweetened beverages.

With ultra-processed foods accounting for more than half of daily energy intake in some populations, the findings highlight diet quality as a potentially modifiable factor in reducing the combined burden of chronic disease.

🔗 Read the full article here: https://mindd.org/research/10-1016-j-lanepe-2023-100771/

Has the growing research on ultra-processed foods changed the way you think about food choices? Let us know below.

18/10/2026

💊 The effects of some medications on the gut microbiome may persist long after they are taken.

A study of more than 2,500 adults found that previous medication use was consistently associated with differences in gut microbial composition — suggesting our medication history may help shape the microbiome we have today.

Long-term effects were detected across several commonly used drug classes, including antibiotics, antidepressants, psycholeptics, proton pump inhibitors and beta-blockers.

Researchers also found stronger associations among people with greater cumulative medication exposure, suggesting repeated or prolonged use may have a greater influence on gut microbial ecology.

While the study was observational and cannot establish cause and effect, the findings add to growing evidence that the gut microbiome may reflect not only current medication use, diet and lifestyle, but past exposures too.

🔗 Read the full article here: https://mindd.org/research/10-1128-msystems-00541-25/

16/10/2026

🧠 Could nutrition play a greater role in neurodevelopmental conditions than previously recognised?

A new narrative review examining autism, ADHD, Down syndrome, intellectual disability and epilepsy highlights the close relationship between nutritional status and symptoms associated with these conditions.

Researchers found that nutrient deficiencies, selective eating, gastrointestinal issues and metabolic differences are common across neurodevelopmental conditions. The review also identified evidence of benefits from specific nutritional interventions, including:
• Vitamin D supplementation in autism, associated with reduced inflammatory markers and behavioural improvements
• Vitamin D combined with magnesium in ADHD, associated with improved behaviour
• Ketogenic diets in epilepsy, consistently associated with reduced seizures
• Combined vitamin D, DHA and L-carnosine supplementation in Down syndrome, associated with gains in communication and motor development

Deficiencies in nutrients including vitamin D, omega-3 fatty acids, iron, zinc and magnesium may also contribute to neuroinflammation and oxidative stress.

The researchers conclude that nutrition is an important component of neurodevelopmental health and call for greater research into nutrition-based approaches.

🔗 Read the full article here: https://mindd.org/research/10-1007-s44187-026-00804-4/

14/10/2026

🧠 Alzheimer’s disease can begin developing decades before symptoms appear — raising an important question: can we intervene earlier?

A clinical framework paper describes how two Alzheimer’s Prevention Clinics are using personalised, precision-medicine approaches to identify and address risk well before dementia develops.

Each patient undergoes a detailed assessment incorporating medical history, lifestyle and genetic factors. Rather than following a single standardised program, interventions are tailored to the individual and may include nutrition counselling, physical activity, supplements and management of metabolic or vascular conditions.
This approach reflects growing evidence that many Alzheimer’s risk factors are modifiable. Hypertension, insulin resistance and physical inactivity can contribute to pathways implicated in Alzheimer’s disease, including inflammation, glucose dysregulation and amyloid accumulation.

Early observations from the clinics suggest patients can engage successfully with long-term preventive care and show measurable improvements in cognition and Alzheimer’s-related biomarkers.

The authors now propose larger, multi-site research to determine the effectiveness of personalised Alzheimer’s prevention strategies.

🔗 Read the full article: https://mindd.org/research/10-1016-j-jalz-2018-08-004/

Should personalised Alzheimer’s risk assessment become a greater part of preventive healthcare? Share your thoughts below.

12/10/2026

💡 Do we become less curious as we age? New research suggests the answer depends on what kind of curiosity we’re talking about.

A study of more than 1,200 adults aged 20–84 found that trait curiosity — our general tendency to seek out new knowledge — decreased with age.
But state curiosity, the momentary desire to find out specific information, actually increased.

Older adults displayed greater moment-to-moment curiosity despite correctly guessing fewer answers to trivia questions. Further analysis found that middle-aged adults had the lowest levels of state curiosity, while older adults had the highest.
One possible explanation is that our growing knowledge base changes how we engage with new information. As we age, information that connects with what we already know may become particularly effective at sparking curiosity.

The findings suggest curiosity doesn’t simply disappear with age — different forms of it may follow very different trajectories across the lifespan.

🔗 Read the full article: https://mindd.org/research/10-1371-journal-pone-0320600/

12/10/2026

Early Bird tickets to the Mindd International Forum 2027 Practitioner Training are now available!

For a limited time, we are offering discounted Early Bird tickets. For 15% off use code: MINDD27.

Join us at MIF27: A Roadmap for Healing Chronic Conditions—led by Dr. Bruce Hoffman—bringing together global experts in functional healthcare to explore integrative therapies for complex chronic conditions.
🗓️ 30 April – 1 May 2027
📍 Sydney, Australia

Train with Global Experts in Functional Healthcare—experienced clinicians will present case studies supporting the Seven Stages Masterclass, exploring the challenges of treating complex patients and a layered, hierarchical roadmap for healing.

Explore approaches including:
• Chiropractic
• Family Constellation
• Functional Medicine
• Mitochondrial Therapies
• Naturopathy & Nutrition
• Osteopathy
• Psychospirituality
• Quantum Dentistry
• Applied Psycho Neurobiology

Gain practical insights into:
• Treatment sequencing and the hierarchy of biological needs
• Cellular mechanics and the Cell Danger Response
• Subconscious emotions, personality and ego
• Circadian biology and EMFs
• Environmental toxicity
• Generational stress and epigenetics
• Psychospiritual factors that influence healing
Explore case studies spanning ADHD, autism, anxiety, autoimmune conditions, CFS, Crohn’s, depression, Long Covid, Lyme, MCAS, mould/CIRS, PANS, Parkinson’s, POTS, sleep disorders and more.

🎟️ Practitioners can register now at mif27.mindd.org
⭐ Mindd Practitioners: check your email for a special 20% discount code.

11/10/2026

🧠🦠 What does current research actually tell us about the gut-brain axis in autism and ADHD?

A new narrative review suggests that changes in the gut microbiome may influence how symptoms present—particularly in autism.

The review examined human research into the gut-brain axis, which connects the gut and brain through immune, endocrine and neural pathways.

In autism, studies have reported associations between the gut microbiome, gastrointestinal symptoms, intestinal permeability, immune activation, diet and symptom severity. However, findings remain inconsistent, and researchers have not identified a specific microbial pattern associated with autism.

Research into ADHD and the gut microbiome remains more limited and largely exploratory.

Gut-directed interventions, including probiotics and microbiota transfer therapy, have shown more consistent improvements in gastrointestinal symptoms than in core autism features, with benefits most apparent among individuals experiencing significant gastrointestinal issues.

The findings highlight the complexity of the gut-brain relationship — and how much remains to be understood.

🔗 Read the full article: https://mindd.org/research/10-3389-frcha-2026-1835043/

What questions would you like to see future gut-brain research answer? Let us know below.

07/10/2026

🎟️ WIN A FREE PASS TO THE MINDD INTERNATIONAL FORUM 2027!

🧠 Different Brains, Different Burdens with Dr Michelle Clark, ND

Differences in brain function and individual neurobiology can influence how people experience symptoms, health challenges and the demands of everyday life.

In this free webinar, Dr Michelle Clark explores why two people exposed to similar physical, emotional or environmental demands may experience very different levels of burden. She discusses the importance of considering individual neurobiology when assessing patients and how a more personalised perspective can help practitioners move beyond a one-size-fits-all approach to care.

🔬 The webinar explores how individual differences may influence health experiences and symptoms, why patients can respond differently to similar stressors, and how these insights can inform more individualised clinical strategies.

Dr Clark brings more than 25 years of experience across primary care, health policy, practitioner education and industry innovation, with a particular focus on functional genomics and translating individual genetic information into personalised clinical strategies.

🎥 The free webinar recording is now available in the Mindd Health Hub.

💬 Watch the recording before joining Dr Clark for a Live Q&A on October 8 at 7pm AEDT, where attendees can ask questions and explore the clinical applications of the presentation in greater depth.

🎟️ Live Q&A attendees will also go into the draw to win a FREE pass to the Mindd International Forum 2027!

Access the webinar and Live Q&A via the link in bio. /

Access the webinar here: https://educationhub.mindd.org/webinars/different-brains-different-burdens/?mc_cid=0ed6b1f839&mc_eid=d0998b36b9

Tune into the Live Q&A here: https://us02web.zoom.us/j/84495325192?mc_cid=0ed6b1f839&mc_eid=d0998b36b9

Get your tickets for MIF27 here: https://mif27.mindd.org

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