09/09/2026
🚨 NEWS: Could Tylenol/Acetaminophen use in pregnancy impact future reproductive health in girls?
It's a discussion worth having BUT it doesn't yet change practice guidelines. Why? Benefit vs risk.
Tylenol has long been labeled safe for use in pregnancy. But we have always encouraged using only as indicted. Using medication when not clearly warranted creates a potential risk exposure without clear benefit.
Another reason for no changes is this was a very small sample of women within a small demographic. Less than 700 women from Denmark.
"The study found that girls exposed to acetaminophen in the womb had, on average, 40% smaller ovarian volume, 13% smaller uterine volume and 23% fewer ovarian follicles — the structures that contain immature eggs — compared with girls whose mothers did not use acetaminophen during pregnancy. They also showed lower levels of a hormone linked to ovarian reserve."
Those results warrant more research but it isn't enough to say never use Tylenol. Why?
"Acetaminophen has long been known as the safest over-the-counter option to treat fever or pain during pregnancy, although doctors advise using it in moderation and only when necessary. An untreated fever can endanger both mother and fetus, possibly leading tobirth defects
ormiscarriage."
This is where the benefit risk balance occurs. If you have a very mild ache where rest, ice, etc., might help, it could be worth trying that before grabbing Tylenol. However, if you have a fever, we knows fevers themselves can cause serious complications in pregnancy thus making the benefit of Tylenol worth these potential unknown risks.
Short version, a small study shows a possible risk with Tylenol use. Maybe don't grab Tylenol as a first cure all for discomfort. But, when indicated for true pain or fevers, it has known benefits which outweigh unknown risks.
If you have concerns about medication, always check with your midwife, doctor, or pharmacist.
.